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Boiling point:170-171 °C(lit.)
Density 1.2 g/mL at 25 °C(lit.)
refractive index n20/D 1.402(lit.)
Flash point:71 °C
form Colorless liquid with a mild odor
Water Solubility Soluble in water.
Dimethyl phosphite may be used as an effective alternative to organic tin hydrides as radical reducing agents for organic halides, thionoesters, and isocyanides to form the corresponding hydrocarbons. Radical translocation/cyclization reactions of terminal alkynes to form cyclic phosphonates can also be effectively carried using dimethyl phosphite as a reagent under tin-free condition.
Dimethyl phosphite is used in the synthesis of α-aminophosphonates, which are medicinally important phosphorus analogs of amino acids, by treating with an amine and an aldehyde or a ketone. It can also be employed in asymmetric hydrophosphonylation of aldehydes to synthesize optically active α-hydroxy phosphonates.
Boiling point:170-171 °C(lit.)
Density 1.2 g/mL at 25 °C(lit.)
refractive index n20/D 1.402(lit.)
Flash point:71 °C
form Colorless liquid with a mild odor
Water Solubility Soluble in water.
Sensitive Moisture Sensitive
BRN 1697490
Stability:Stable. Moisture sensitive. Incompatible with water, strong oxidizing agents, acid chlorides, strong bases.
CAS DataBase Reference868-85-9(CAS DataBase Reference)
FDA UNIIST4TBO000H
IARC3 (Vol. 48, 71) 1999
NIST Chemistry ReferencePhosphonic acid, dimethyl ester(868-85-9)
EPA Substance Registry SystemDimethyl phosphite (868-85-9)
1. Dimethyl phosphite can be directly used to synthesize organophosphorus insecticide trichlorfon, herbicide glyphosate, etc. on pesticides, and can also be used to synthesize other phosphorus-containing intermediates, such as O,O-dimethylphosphorus Acid chloride, O, O-dimethyl thio(alcohol) ammonium phosphate, etc. In addition, it is also an important organic synthetic raw material for the production of organic phosphoric acid corrosion inhibitors, plastic additives, dye additives and textile Chemicalbook flame retardants.
2. Used as lubricant additives, adhesives and some organic synthesis intermediates. Used in the synthesis of insecticides omethoate, methyl thiocyclophosphate and herbicide glyphosate, etc.
3. This product is an important intermediate for pesticides such as solid glyphosate, trichlorfon, dichlorvos, dimethoate, omethoate, etc.; also used in organic phosphoric acid corrosion inhibitors, plastic additives, dye additives and flame retardants Production.
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