Silibinin

What is Silibinin?

Silibinin (INN), also known as silybin (both from Silybum, the generic name of the plant from which it is extracted), is the major active constituent of silymarin, a standardized extract of the milk thistle seeds, containing a mixture of flavonolignans consisting of silibinin, isosilibinin, silychristin, silidianin, and others. Silibinin itself is a mixture of two diastereomers, silybin A and silybin B, in approximately equimolar ratio. The mixture exhibits a number of pharmacological effects, particularly in the fatty liver, non-alcoholic fatty liver, non-alcoholic steatohepatitis, and there is great clinical evidence for the use of silibinin as a supportive element in alcoholic and Child–Pugh grade ‘A’ liver cirrhosis.

However, despite its several beneficial effects on the liver, silibinin and all the other compounds found in silymarin, especially silychristin seem to act as potent disruptors of the thyroid system by blocking the MCT8 transporter.[3] The long term intake of silymarin can lead to some form of thyroid disease and if taken during pregnancy, silymarin can cause the development of the Allan–Herndon–Dudley syndrome. Although this information is unfortunately still not being taken into consideration by all regulatory bodies, several studies now consider silymarin and especially silychristin to be important inhibitors of the MCT8 transporter and a potential disruptor of the thyroid hormone functions.

Basic Information:

Benefits of Silibinin

Silibinin may be beneficial to dogs with liver problems.

Silymarin is the part of the plant that has the beneficial properties.

Silibinin milk thistle for dogs comes in capsules, liquid, or powder forms.

While silibinin may benefit a dog’s liver, they won’t cure diseases.

Pet owners should speak to a veterinarian before giving a silibinin supplement to their dogs.

Use：

The active ingredient in silymarin powder is silymarin, a natural flavonoid lignan compound, which mainly contains silybin, isosilybin, silymarin and silymarin. Construct, in which silibinin has the highest content and the highest hepatoprotective activity. At present, the role of medicinal bulk milk thistle powder is mainly reflected in:

1. Silymarin powder is sometimes used as a natural remedy for liver problems.

2. Anti-cardiovascular disease effect. Silymarin extract powder can lower cholesterol levels and has cardiovascular benefits.

3. Directly remove reactive oxygen species, resist lipid peroxidation, and maintain the fluidity of cell membranes.

4. Protects against cerebral ischemia injury.

The Silibinin Supplier

Green Agri enjoys long term relationships with our clients because we focus on customer service and providing great products. If you are interested in our products, we are flexible with the customization of orders to suit your specific need and our quick lead time on orders guarantees you’ll have great tasting our products on-time.

We also focus on value-added services. We are available for service questions and information to support your business.

Why Choose Silibinin?

Green Agri specialize in silibinin milk thistle for several years, we supply products with competitive price, and our product is of the highest quality and undergoes strict, independent testing to ensure that it is safe for consumption around the world.

Where to buy Silibinin?

Just send email to info@greenagribio.com , or submit your requirement in bottom form, we are of service at any time!

Why choose us?

• If you’re looking for reliable Botanical Feed Additives, look no further – we have what you need.
• We abide by the ethical code of ‘ruling the enterprise by virtue, honesty and trustworthiness’, insist that product quality is the life of the enterprise, and the business policy of high-quality service creates the future.
• With our Botanical Feed Additives, you can be sure that you’re getting the best quality and value for your money.
• Our Silibinin not only have a good reputation in China, but also are exported to many countries and regions.
• Our team has years of experience in producing high-quality Botanical Feed Additives, ensuring you get the best possible product.
• ‘Based on domestic market and expand overseas business’ is our development strategy for Silibinin.
• Our Botanical Feed Additives are made using advanced manufacturing techniques, ensuring consistent quality and effectiveness.
• We are a technology-driven company focusing on promoting the update and upgrade of the Silibinin.
• Our Botanical Feed Additives are formulated to be effective and easy to use, making them the perfect addition to any animal feed.
• We believe it is very important to treat people sincerely, be honest and trustworthy, and perform our duties with reverence. And it is our corporate value to face challenges, dare to be the first and rise to the occasion!

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