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Product Name:Polygonatum Root Powder
Appearance:Brown yellow powder
Specification:10:1
Test Method:UV
Advantage: bulk stock in USA warehouse;
Certificate: KOSHER, HALAL, ISO,ORGANIC CERTIFICATE;
Polygonatum root powder has hypoglycemic and anti-oxidative stress effects, has obvious protective effect on islet B cell damage in diabetic rats induced by alloxan, improves the body weight of diabetic rats in a dose-dependent manner, and reduces fasting. Blood sugar and pancreatic tissue MDA content, enhanced SOD, GSH-Px, CAT activity.
Polygonatum powder can reduce blood glucose in type Ⅰ diabetic mice by restoring the balance of CD4+ and CD8+ T lymphocyte subsets and regulating the level of cytokines during the pathogenesis.
The total polygonatum officinale rhizome/root extract and its chloroform separated parts have obvious hypoglycemic effect, and have obvious protective effect on kidney disease, and the chloroform separated part lasts longer. The total saponins of Polygonatum japonica reduce the blood sugar of mice with alloxan-induced hyperglycemia by inhibiting the activity of α-glucosidase.
Product name |
Polygonatum Polysaccharide |
Latin name |
Rhizoma Polygonati Extract |
Part used |
Root & Stem |
Extraction Type |
Solvent Extraction |
Active Ingrdients |
Polysaccharide |
Synonyms |
Dragon rank, sun grass, white and wild ginger |
Test Method |
UV |
Specifications |
Polysaccharide 10%-50%, 10:1 Brown yellow powder |
Application |
Medicine, food additives |
Antioxidative effect
The monomer compounds of polygonatum root powder ferulic acid tyramide and high isoflavone have obvious protective effects on the damage of PC12 cells by oxygen free radicals, and the cell survival rate is significantly increased. Polygonatum japonica water extract can reduce the damage of medium-wave ultraviolet rays to keratinocytes to a certain extent, and inhibit the decline of fibroblast activity caused by long-wave ultraviolet rays.
2. Immunomodulatory effect
Polygonatum root powder can enhance immune function, improve thymus, spleen quality, macrophage phagocytosis percentage and phagocytosis index of cyclophosphamide-induced immunocompromised model mice, promote hemolysin, hemolytic plaque formation, and increase lymphocytes Conversion rate. Polygonatum japonica extract can significantly inhibit the transformation and proliferation of T lymphocytes, reduce the release of the liver injury cytokine Chemicalbook, in a dose-dependent manner, thereby exerting a protective effect on the liver.
3. Anti-tumor effect
Polygonatum powder has significant anti-tumor effect, can inhibit the proliferation of human esophageal cancer cells Eca-109, and induce its apoptosis, can promote tumor-bearing mouse cells to secrete IL-2 and peritoneal macrophages It secretes IL-1 and TNF-α to enhance cellular immune function, and directly induce tumor cell apoptosis to promote human colon cancer CL-187 cell apoptosis.
4. Anti-aging effect
Polysaccharide polysaccharide can increase the activity of serum superoxide dismutase in aging mice, enhance the scavenging ability of free radicals, inhibit lipid peroxidation, reduce the content of MDA, and at the same time its immune function in subacute aging mice It has a certain regulatory effect, can improve immune imbalance, enhance cellular and humoral immune function, thereby delaying aging. Polygonatum officinale rhizome/root extract can alleviate the oxidative damage of D-galactose-induced subacute aging mouse model, protect the mitochondrial DNA of liver cells, and delay the aging of the body.
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