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Product Name: Rhubarb extract
Latin Name: Rheum palmatum L.
Ingredient:Emodin 50% 98%;
Appearance: Yellow Powder;
Test Method: HPLC TLC;
Application:animal remedy additives
Advantage: bulk stock in USA warehouse;
Certificate: KOSHER, HALAL, ISO,ORGANIC CERTIFICATE;
Rhubarb extract is a plant. The root and underground stem (rhizome) are used to make animal medicine. The stalk of rhubarb extract is also consumed as food. Traditional Chinese medicine commonly uses rhubarb extract powder alone or in combination with other ingredients.
Chinese rhubarb extract is used for digestive complaints including constipation, diarrhea, or stomach pain, symptoms of menopause, menstrual cramps (dysmenorrhea), swelling (inflammation) of the pancreas, and many other conditions, but there is no good scientific evidence to support these uses.
Name: |
Rhubarb Extract |
CAS No: |
518-82-1 |
Appearance: |
yellow needle crystal powder |
Molecular Formula: |
C15H10O5 |
Molecular Weight: |
270.23 |
Herb Sourse: |
rhubarb |
Part used: |
root |
Spec: |
98% |
Testing method: |
HPLC |
Active ingredient: |
Emodin |
Particle size: |
100% pass 80 mesh |
EINECS: |
208-258-8 |
Shelf Life: |
2 years if properly stored. |
Storage: |
Cool and dry place,keep away from strong light & high temp |
Package: |
25kg /drum,or as per customer’s requests. |
This study was designed to evaluate the clinical efficacy and safety of Rhubarb extracts in dogs with chronic renal failure (CRF). Client-owned 40 dogs with CRF graded International renal interest Society (IRIS) II-III were enrolled in this study. The dogs were equally allocated and blindly administered with or placebo. The following items were evaluated at day 0, 30, 90 and 180: body condition score (BCS), clinical score (appetite, polydipsia/polyuria, quality of life score), hemogram (WBC, RBC, PCV), serum biochemistry (ALT/AST, ALP, Creatinine/BUN, total protein, albumin), serum electrolyte (Na, K, Cl, Ca, P), systolic blood pressure, urinalysis (UPC, USG) and IRIS stage.
In this study, we found that the preparation was well tolerated by dogs and induced no adverse effects. Statistically significant improvements were observed in clinical score (quality of life score by vet and clients), serum BUN and creatinine levels, serum phosphorus concentration, level of proteinuria, and the IRIS score of CRF in dogs after 6 month of treatment of chinese rhubarb extract.
Those findings suggested that the Rhubarb extracts can improve the clinical signs of CRF (i.e. azotemia, hypertension, proteinuria, hyperphosphoremia) and the quality of life (i.e. BCS, clinical score) and can retard the progression of CRF in dogs. Therefore the rhubarb extract powder can be a good supplementary drug for treating dogs with subclinical and clinical renal diseases. However, care should be taken for interpreting our result, because this study is not double-blinded controlled study but pilot study.
Rhubarb extract powder is extensively used in traditional Chinese medicine. Rhubarb has been studied for the management of GI and renal function disorders, and for the treatment of hyperlipidemia, cancer, and acute ischemic stroke. However, sound clinical evidence for its use is lacking.
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