Magnolia Extract

What is Magnolia Extract?

Magnolia extract is a plant tracked down in pieces of Asia and North and South America. Traditional Chinese medicine uses the flowers and bark.

Magnolia appears to have uneasiness decreasing impacts. The chemicals in magnolia may kill bacteria in the mouth, thereby reducing gum swelling and preventing cavities.

Magnolia bark extract powder is used to treat depression and anxiety as well as the “stagnation of qi” in Traditional Chinese Medicine. In addition, magnolia is used to treat obesity, stress, gingivitis, plaque, and other conditions; however, the majority of these uses are not supported by sound scientific evidence.

Basic Information:

Magnolia Extract Benefits:

Magnolia extract is a popular herbal remedy used to treat a variety of health conditions in dogs. It is thought to be effective in relieving anxiety, improving digestion, and reducing inflammation. Magnolia bark is available in powder, capsule, and tincture form. The recommended dose of magnolia bark for dogs is 0.5-1 mg/lb body weight given 2-3 times daily.

1 Antibacterial effect

  Magnolia officinalis has strong antibacterial effect. Lu Jinqing (1989) found that Magnolia officinalis decoction was effective against Shigella, Typhoid Bacillus, Paratyphoid Bacillus, Orphanus cholerae, Bacillus subtilis, Escherichia coli, Trichophyton mentagrophytes, Proteus, Pseudomonas aeruginosa and Staphylococcus aureus, Streptococcus hemolyticus, Diplococcus pneumoniae, Bacillus pertussis and other bacteria have strong antibacterial effect. Its alcohol extract also has a strong inhibitory effect on skin fungi and Mycobacterium tuberculosis. Magnolia bark extract has antibacterial activity against Bacillus anthracis in vivo.

2.Antioxidant effect

  Both magnolol and honokiol in magnolia bark have strong antioxidant effects. If used as a feed additive, it can protect the vitamins and some active substances in the feed, thereby improving the overall nutritional value of the feed.

3 Anti-ulcer effect

  magnolia bark extract powder has a significant inhibitory effect on mucosal ulcers. Magnolol has inhibitory effects on pyloric ligation, water immersion stress gastric ulcer, and duodenal spasm induced by histamine (Wang Chengnan and Xia Chuangge. 2003).

  Kazuo Watanabe (1979) used a variety of experimental ulcer animal models and gastric acid secretion assays to find that the active ingredients of magnolia extract had significant activity on gastric acid secretion and experimental ulcers. It can treat chest and abdomen fullness of the digestive system and gastrointestinal neurosis. It also has the effect of preventing stress gastric dysfunction. From the investigation of the pharmacological effects of digestive organs, the active ingredients of Magnolia officinalis have significant mediating effect and anti-ulcer activity on isolated intestines of rats and guinea pigs. And it has obvious preventive effect on rats’ fecal ulcer, and the effective concentration of anti-ulcer effect is 5-200 mg/kg (Lu Jinqing, 1989).

4. Muscle relaxation and sedation

  Magnolol and honokiol have long-lasting central muscle relaxation. Watanbe et al. (1975) found that magnolol and honokiol, the active ingredients of magnolia bark, have a special and lasting muscle relaxation effect. In the net climbing test of rats, intraperitoneal injection of 100 mg/kg can produce obvious muscle relaxation for 2 hours, and when the dose is increased to 250 mg/kg, some mice can lose the righting reflex and lengthen the muscles. Loose effect more than 3 h. The effect gradually disappeared 24 hours after injection, the minimum effective dose was 90 mg/kg, and the effective dose of sedative effect was even smaller.

Application of Magnolia officinalis in Animals

  Houcun, the application in animals is mainly through some drug experiments on mice, these experiments reflect the medicinal value of l『Magnolia officinalis. Huang Debin et al. (2005) found that the inhibitory effect of honokiol and honokiol on B-endorphin in alleviating the morphine withdrawal reaction in rats was significantly higher than that of honokiol and honokiol. saline group, and the inhibitory effect of honokiol was higher than that of magnolol. Zhu Ziping (1998) fed different proportions of magnolia bark extract to mice, and found that magnolia extract had obvious analgesic effect, and could significantly reduce the increase of peritoneal capillary permeability of mice caused by acetic acid , and significantly inhibited xylene-induced mouse ear swelling and mouse toe swelling. Li Jieping et al. (2003) found that inhibiting the release of lysosomal enzymes may be one of the anti-inflammatory mechanisms of magnolol in the effect of magnolol on the function of rat neutrophils activated by chemotactic tripeptides.

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