Methionine Hydroxy Analogue

What is methionine hydroxy analogue?

Hydroxy-methyl butyric acid, also known as methionine hydroxy analog (MHA), is used in animal nutrition as an equivalent to methionine, since it is converted into L-methionine by enzymes inside animals’ bodies. … The reaction of MMP and HCN is catalyzed by a mixture of pyridine and acetic acid.

When methionine (Met) is limiting in swine diets, it is commonly supplemented by using anhydrous dl-methionine (DLM, 99% purity) or liquid dl-methionine-hydroxy analogue free acid (MHA-FA, 88% purity). The objective of this experiment was to test the null hypothesis that the bioavailability of DLM and MHA-FA were not different for growing pigs, using the indicator amino acid (AA) (phenylalanine, Phe) oxidation (IAAO) method in a slope-ratio assay. Six barrows (mean BW during study: 21.1 kg) received seven dietary treatments with all pigs receiving all diets in random order at an intake of 95 g/kg BW0.75. 

Analysis:

Uses

Methionine hydroxy analogue is an essential amino acid that cannot be synthesized by animals. Fish meal is rich in methionine, and the methionine content in general plant protein cannot meet the needs of animals, especially the most commonly used soybean meal lacks methionine. Therefore, methionine is an amino acid that is most easily deficient in feed. An additional source of methionine is added to it. Methionine Hydroxy Analogue (MHA), also known as liquid hydroxymethionine or liquid methionine, is a methionine additive. It is a good source of methionine for ruminants, pigs, chickens and aquatic animals.

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